Radiesse®

Go Beyond Collagen Stimulation

What are RADIESSE® and RADIESSE® (+)?
RADIESSE® and RADIESSE® (+) are dermal fillers that are used for smoothing moderate to severe facial wrinkles and folds, such as nasolabial folds (the creases that extend from the corner of your nose to the corner of your mouth). RADIESSE® is also used for correcting volume loss in the back of the hands. RADIESSE® (+) is also used for improving moderate to severe loss of jawline contour in adults over 21 years old.

Radiesse chart
Radiesse
Radiesse

Your Skin Changes Over Time
That’s probably no surprise—but do you know exactly how? Two important components are collagen and elastin, which help keep facial lines and wrinkles at bay. Unfortunately, aging and environmental factors (think sun damage) make it harder for your body to produce collagen and elastin. This can cause facial skin to wrinkle and sag, stealing from your youthful appearance.1,2

CaHA Is the Key
Calcium hydroxylapatite, or CaHA, is what makes Radiesse unique as a dermal filler treatment. Radiesse is composed of CaHA suspended in an aqueous gel carrier.3

Upon injection, the Radiesse CaHA gel matrix provides immediate improvement.1,4,5

CaHA particles form a “scaffold” that stimulates fibroblasts to produce collagen for up to a year and elastin for up to nine months (after only one injection).1,4-8

For immediate, long-term rejuvenation1,7,9:

  • Immediately smooths wrinkles and folds
  • Long-term benefit from the stimulation of new collagen and elastin
Radiesse

References

  1. Yutskovskaya Y, et al. J Drugs Dermatol. 2014;13(9):1047-1052.
  2. Baumann L. J Pathol. 2007;211(2):241-251.
  3. Radiesse [Instructions for use]. Franksville, WI: Merz North America, Inc; 2023.
  4. Tzikas TL. Dermatol Surg. 2008;34 Suppl 1:S9-S15.
  5. Loghem JV, et al. J Clin Aesthet Dermatol. 2015;8(1):38-49.
  6. González N, Goldberg DJ. Dermatol Surg. 2019;45(4):547-551.
  7. Bass LS, et al. Aesthetic Surgery J. 2010;30(2):235-238.
  8. Van Rozelaar L, et al. Aesthet Surg J. 2014;34(1):118-132.
  9. Moers-Carpi M, et al. Dermatol Surg. 2007;33(suppl 2):S144-S151.
  10. Radiesse (+) [Instructions for use]. Franksville, WI: Merz North America, Inc; 2023.